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Advancing Science Through Research
Providing novel therapies to patients in the community setting and participating in landmark clinical trials are core to the mission of The US Oncology Network.
US Oncology Research forms one of the nation’s largest research networks specializing in Phase I–IV oncology clinical trials. Our investigator- and sponsor-initiated trials bring innovative therapies to patients in local communities across the nation. 
Here are a few facts about US Oncology Research:
• US Oncology Research serves approximately 80 practices in 250 locations.
• At any given time, we typically have more than 225 active trials.
• More than 55,000 patients have participated in trials offered by US Oncology Research.
• US Oncology Research has contributed to the development of 46 cancer therapies approved by the FDA.
Research Leadership
US Oncology Research is physician led and physician driven. Physicians select the trials in which they want to enroll patients, based on the community they serve and the scientific merit of the question to be answered in the clinical trial.
Physician leadership of US Oncology Research includes:

US Oncology Research Leaders:
Daniel Von Hoff, M.D.
Chief Scientific Officer, US Oncology Research
Director of the Translational Oncology (Early Phase) Program
Stephen Jones, M.D.
Medical Director, US Oncology Research
Co-chair of the Breast Committee
Disease Committee Chairs:
Breast Cancer
Joyce O’Shaughnessy
Stephen Jones
Frankie A. Holmes
John W. Smith
Developmental Therapeutics
Nicholas Vogelzang
C. Lance Cowey
Parvesh Kumar

Gastrointestinal Cancer
Donald Richards
Thomas Cartwright
Allen Cohn

Genitourinary Cancer
Nicholas Vogelzang
Thomas Hutson
Gynecologic Cancer
Michael Teneriello

Hematologic Cancer
Nicholas DiBella
Kathryn Kolibaba
Jeff Sharman
Lung Cancer
Craig Reynolds
David Smith
Robert Jotte
Translational Oncology Program
Daniel Von Hoff
Carlos Becerra
Radiation Therapy
Vivek Kavadi
Research Leadership Opportunities
US Oncology Research has many research leadership opportunities, including roles as study principal investigators, site research leaders and participation in national disease committees. These roles have been pivotal in making US Oncology Research what it is today.

Publication Assistance
Our biostatistics and medical writing services team assist physicians in taking investigator-initiated trials from concept to publication. US Oncology Research has produced over 57 manuscripts from investigator-initiated studies that have been published in peer-reviewed journals.

US Oncology Research publication and presentation accomplishments from 1999–2010 include:



Posters Oral Presentations
88 54 4
41 28 7
12 3 1
World Lung Cancer
12 9 4
Inv meetings
23 2 16
Pan Pacific
2 1 0
3 2 1
7 6 1
2 2 -
2 - -
TOTAL   192 107 34
Integrating Research and Healthcare Technology
Practices affiliated with US Oncology Research utilize several technological tools to more easily match patients to clinical trials.
iKnowMedTM is an oncology-focused electronic health record (EHR). After the staging and diagnosis process is complete or updated, iKnowMed automatically screens the patient’s record for potential clinical trial eligibility. This helps physicians using iKnowMed increase participation in open clinical trials at their practice, and assists with the selection of the appropriate treatment regimen at the point of care.
The healthcare technology also helps identify patients who may qualify for open trials through US Oncology Research’s Comprehensive Accrual Resource, or “CARE.” At the practice’s request, CARE enables a search of the practice’s patient records in the iKnowMed EHR to find potential matches for open trials at the practice for patients currently on treatment, post-treatment, or even before treatment begins. This resource can help the practice increase accruals while saving valuable time.

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Learn how participating in The US Oncology Network can benefit you and your practice.
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  • US Oncology Research : US Oncology Research is now one of the largest community-based research programs in the U.S. Over the years more than 50,000 patients have participated in over 1,200 clinical trials in our program.
  • Advancing the Science of Care : Investigators in The US Oncology Network advance the science of cancer treatment to enhance patient care.
  • Expanding Patient Access to Quality Care : McKesson Specialty Health and The US Oncology Network will align resources to make sure that patients receive the best care.
  • Emphasis on Clinical Integrity : Physicians and clinicians in The US Oncology Network play an integral role in keeping The Network at the clinical forefront
  • Strengthening Community Care : McKesson Specialty Health President, Marc Owen, discusses the strengths of community-based cancer care.
  • Proving Outcomes with Health Information Technology : Health Information Systems make it possible to prove outcomes in a large patient population
  • Changing Patient Care through the US Oncology Research Network : Dr. Daniel Von Hoff highlights the commitment of the US Oncology Research Network investigators
  • Healthcare Technology Enhancing Quality Patient Care : Improving patient care and safety with an electronic health record
  • What is iKnowMed : How iKnowMed stands out from other Electronic Health Record systems
  • Enabling Personalized Medicine through Network Collaboration : Delivering personalized, precision medicine with the US Oncology Research Network
  • Solutions for the Independent Oncology Practice : Learn how US Oncology can provide varying levels of support to community oncology practices
  • Addressing the Complexities of Cancer Care with an EHR : How an EHR can improve patient care
  • Community Clinical Trials Essential in Delivering Evidence-based Medicine : Learn how evidence-based medicine is impacted by research conducted in the community setting
  • Physician Collaboration to Advance the Science of Cancer Care  : Learn how cross-country collaboration is made possible through the United Network of US Oncology
  • Benefits of Participating in a Nationwide Physician Network : A large network makes it possible to collaborate with experts across the nation on a daily basis
  • Research Needed for Community Oncology to Thrive : Offering Research in the community oncology setting benefits patients
  • Advocating for Pay-for-Performance Opportunities as a United Network : Pay-for-Performance is most likely to happen for a United Network
  • Validating the Value of Level I Pathways : Understanding How Evidence Based Guidelines for Cancer Care Are Developed and What They Mean
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